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Abstract

Chitosan is a linear aminopolysaccharide. Using methods of chemical modification of chitosan, a number of new biologically active materials have been created. The main interest in these products is due to the preservation of the basic physicochemical and biological properties of the original polymer and the acquisition of new properties depending on the nature of the introduced groups. Modified chitosan can be used in various fields such as drug delivery, textiles, wastewater treatment and a number of biomedical applications. The purpose of this work is to extract chitosan from the remains of ApisMellifera bees and synthesize a Schiff base with salicylic aldehyde and glutaraldehyde on its basis , and confirm the structure of the resulting substance using IR spectroscopy. The article presents the results of studying the IR spectra of glutaric and salicylic aldehyde, chitosan Apis mellifera and Chitosan-glutaric, chitosan-salicylic aldehyde. Also presented are studies on the synthesis of chitosan by Apis mellifera using the cryogenic method in liquid nitrogen and its interaction with glutaric and salicylic aldehydes to form a Schiff base .

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17

References

  1. Chitosan/edited by K.G. Skryabina, S.N. Mikhailova, V.P.Varlamova – Moscow: Center “Bioengineering” RAS, 2013. – 593 p.
  2. Ikhtiyarova G.A. Preparation, properties and application of biodegradable polymers of chitin and chitosan / Monograph. Standard polygraph. -2017. P.96.
  3. Vikhoreva G.A., Shablykova E.A., Kildeeva N.R. Modification of chitosan films with glutaraldehyde to regulate their solubility and swelling // Khim. fibers. 2001. No. 3. p. 38-42.
  4. Monteiro, OAC Jr. Some studies of crosslinking chitosan-glutaraldehyde interaction in a homogeneous system / OAC Monteiro Jr., C. Airoldi // International Journal of Biological Macromolecules. 1999. Vol. 26. – P. 119–128.
  5. Fen, YW Optical Properties of Crosslinked Chitosan Thin Film with Glutaraldehyde Using Surface Plasmon Resonance Technique / YW Fen, WMM Yunus, MM Moksin, ZA Talib, NA Yusof // American J. of Engineering and Applied Sciences. – 2011. – Vol. 4, No. 1. – R. 61-65.
  6. Ramachandran, S. Formulation and Characterization of Glutaraldehyde Cross-Linked Chitosan Biodegradable Microspheres Loaded with Famotidine / S. Ramachandran, S. Nandhakumar, MD Dhanaraju // Tropical Journal of Pharmaceutical Research. – 2011. Vol. 10, No. 3. – R. 309-316.
  7. Singh, B. Chemical modification of chitosan with pH-sensitive molecules and specific ligands for efficient DNA transfection and RNA silencing // Journal of nanoscience and nanotechnology. – 2014. – T. 14. No. 1. – S. 564-576.
  8. Jiao, T. F. Synthesis and Characterization of Chitosan-based Schiff Base Compounds with Aromatic Substituent Groups / T. F. Jiao [et al.] i / Iranian Polymer Journal. – 2011. Vol. 20, No. 2. – R. 123-136.
  9. Dua, Y. Preparation of Modified Chitosan By Salicylaldehyde / Y. Dua [et al.] // International Conference on Electronic & Mechanical Engineering and Information Technology. – 2011. – R. 2908-2911.
  10. Jiao, T. F. Synthesis and Characterization of Chitosan-based Schiff Base Compounds with Aromatic Substituent Groups / T. F. Jiao [et al.] / Iranian Polymer Journal. – 2011. – Vol. 20, No. 2. – R. 123-136.
  11. Guinesi, LS Influence of some reactional parameters on the substitution degree of biopolymeric Schiff bases prepared from chitosan and salicylaldehyde / LS Guinesi, ETG Cavalheiro // Carbohydrate Polymers. 2006. – Vol. 65. – P. 557–561.
  12. Jones P., Sandorfi K. Application of spectroscopy in chemistry. M. Foreign publishing house. lit., 1959. - 209 s.
  13. P.E. Ignatieva, E.S. Zhavoronok O.A. Legonkova, S.A. Kedik Compositions based on aqueous solutions of chitosan and glutar aldehyde for embolization of blood vessels. Тонкие химические технологии / Fine Chemical Technologies. 2019 v.14 №1.
  14. Mengliev A.S., Ikhtiyarova G.A. Preparation of azomethine derivatives (schif bases) chitosan apis mellifera/ Technical science and innovation. No. 4/2022 y.pp.24-29.
  15. Ikhtiyarova G.A., Mengliev A.S., Ulashev Sh.M. Selection of chitosan by cryogenic method from bee deaths and synthesis of schiff base based on salicyaldehyde and its use in fabric dying. Scientific journal “Oil and Gas”.publications of KKSNVO MNVO of the Republic of Kazakhstan .
  16. Ulashev Sh., Ikhtiyarova G.A. Study of the interaction of the aminopolysaccharide chitosan Apis mellifera with glutaraldehyde // Composite Materials. – 2024. – No. 1. (in Rus)

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